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"I think you guys [gals ?] are the best. Free shipping on hammer products and super fast service. What's not to like?"

Nancy H.

Dear,

Proline Sports Nutrition & Equipment,

I was shopping for the product below using Google as which time I saw your Google add. This was the first I heard of your company. I went to your site and liked what I saw and proceeded to order the Optygen HP. The order was placed on late Friday afternoon and was delivered (to my surprise) on Saturday. Your service is awesome as well as your price match guarantee. There is no doubt that I will continue to use you in the future, as well as recommend you to others.

Regards,

Brian H
Aurora, IL

I am very impressed with your customer service. I was worried about getting my order with a marathon a week and a half out. Wow, less than 24 hours and my order was sitting on the porch. That is phenominal service. I will definately shop with you again. I have had free shipping take 10 days. Proline Sports Nutrition is a site I will recommend to my many running/cycling buddies. Thanks for the great response. BTW, that info on the Hammer Nutrition products was wonderful!! It helped me hone in on my nutrition/hydration plan for my marathon. I printed off the entire 120 pages! This is my 4th marathon. I've trained hard, and my Hammer plan I do believe will give me a PR.

Beta-Alanine

Beta-alanine


Beta-alanine
Systematic (IUPAC) name
3-aminopropanoic acid
Identifiers
PubChem	239
Chemical data
Formula	C₃H₇NO₂
Molar mass	89.093
SMILES	C(CN)C(=O)O
Complete data

In biochemistry, beta-alanine is the only naturally occurring beta amino acid, which are amino acids in which the amino group is at the �-position from the carboxylate group (i.e., two atoms away, see Figure 1). The IUPAC name for �-alanine would be 3-aminopropionic acid. Unlike its normal counterpart, L-�-alanine, �-alanine has no chiral center.

�-alanine is not used in the biosynthesis of any major proteins or enzymes. It is formed in vivo by the degradation of dihydrouracil and carnosine. It is a component of the naturally occurring peptides carnosine and anserine and also of pantothenic acid (Vitamin B-5) which itself is a component of coenzyme A. Under normal conditions, beta-alanine is metabolized into acetic acid.

�-alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available �-alanine. Supplementation with �-alanine has been shown to increase the concentration of carnosine in muscles, decrease fatigue in athletes and increase total muscular work done.^[1]^[2]

Even though much weaker than glycine(and thus with a debated role as a physiological transmitter), beta alanine is an agonist next in activity to the cognate ligant glycine itself, for strychnine-sensitive inhibitory glycine receptors (GlyRs) (the agonist order: glycine>>b-alanine>taurine>>lalanine, l-serine>proline).^[3]

References

^ Derave W, Ozdemir MS, Harris R, Pottier A, Reyngoudt H, Koppo K, Wise JA, Achten E. (Aug 9). "Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters". J Appl Physiol. PMID 17690198.
^ Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA. (2007). "Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity". Amino Acids 32 (2): 225-33. PMID 16868650.
^ Encyclopedia of Life Sciences Amino Acid Neurotransmitters Jeremy M Henley, University of Bristol, Bristol, UK Copyright � 2001 John Wiley & Sons, Ltd. All rights reserved. DOI: 10.1038/npg.els.0000010 Article Online Posting Date: April 19, 2001

Credit: http://en.wikipedia.org/wiki/Beta-alanine